Podcast Episode

🔥 The 25% Effect: Retatrutide Redefines Weight Loss

Dr RR Baliga's "Got Knowledge Doc" Podkast·Dr RR Baliga, MD, MBA·8 October 2026·2 min

About this episode

In TRIUMPH-1, once-weekly retatrutide produced mean weight loss of up to 25% at 80 weeks—but the story extends beyond the scale. ⚖️ 🦵 Less knee osteoarthritis pain 😴 Fewer obstructive sleep apnea events ❤️ Improved cardiometabolic measures 🩸 89–93% with prediabetes reverted to normoglycemia A triple GIP/GLP-1/glucagon receptor agonist may reshape how we think about obesity: not simply kilograms lost, but disease burden reduced. 💡 ⚠️ Gastrointestinal adverse effects remain important.