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Podcast Episode

Can a Dementia Drug Help Your Long COVID Brain Fog? with Evan H. Hirsch, MD

EnergyMD Podcast··31 August 2026·8 min

About this episode

A new analysis out of Japan says a dementia drug might ease Long COVID fatigue and depression. But it's basically a reanalysis of the same trial that already failed back in 2025, and even where it helped, results were mixed. The reanalysis splits people by whether they had a reactivated herpesvirus. Evan H. Hirsch, MD breaks down what that virus is actually doing to your brain, why the drug only helped part of the group and made others worse, and why chasing one virus and one brain chemical never gets to the real cause. He also shares how a client recovered by addressing all of the Toxic 5, the five root causes behind almost every case of Long COVID and chronic fatigue. In this episode, you'll learn: Why the new Japan analysis is actually a reanalysis of the same JAMA trial that already found no benefit in 110 people, and why results stayed mixed even where it helped How HHV6B, a herpesvirus that reactivates after COVID, produces a protein called SITH1 that drains acetylcholine and drives brain fog Why treating one reactivated virus or one brain chemical never resolves Long COVID on its own What the Toxic 5 are, and why nervous system dysfunction, what Dr. Patrick Porter calls neurological lock, is one of the five root causes How a client recovered by addressing all five root causes together, not just the reactivated virus driving her brain fog Discover your fatigue score and the root causes keeping you stuck: https://myfatiguescore.com Free Fatigue Masterclass: https://fixyourfatigue.com See real results: https://energymdmethod.com/results Chapters: 00:00 - Introduction 00:25 - What the New Japan Analysis Found 01:39 - Why the Results Were Still Mixed 02:17 - Why Donepezil Misses the Bigger Picture 02:54 - The Toxic 5 and Neurological Lock 04:08 - Case Study: A Client's Recovery 05:55 - Why Full Recovery Takes Time Subscribe to the EnergyMD Podcast for weekly conversations with leading experts on resolving ME/CFS and Long COVID by addressing the real root causes. . For more information about Evan and his program, Click Here. Prefer to watch on Youtube? Click Here. Please note that any information in this episode is for educational purposes only and does not constitute medical advice.