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Podcast Episode

Ep 48. One Shot at a New Life with Gene Therapy Patient Brian O'Mahoney

Let's Talk SADS Live··14 April 2026·36 min

About this episode

Gene therapy. One injection. No going back. Brian O'Mahoney, the first person in Ireland to receive any gene therapy, has lived with severe hemophilia B his entire life. In this deeply personal conversation, Brian shares what it really means to make an irreversible medical decision, and how basing his choice on data from just three patients became the leap of faith that changed everything. Now, 44 years into leading patient advocacy across Ireland, Europe, and globally, Brian is helping others navigate the same impossible question: When do you take the one shot you'll ever get? This episode offers a rare look inside the mind of someone who chose to rewrite their own biology, and the resilience required to help an entire community do the same. Watch the full episode and follow us on our socials! Facebook - https://tinyurl.com/CanadianSADSFacebook YouTube - https://tinyurl.com/CanadianSADSYouTube Instagram - https://tinyurl.com/CanadianSADSInstagram Spotify - https://tinyurl.com/CanadianSADSSpotify Apple - https://tinyurl.com/CanadianSADSApple Amazon - https://tinyurl.com/CanadianSADSAmazon #LetsTalkSADSLive #SADS #GeneTherapy #Hemophilia #HemophiliaB #PatientAdvocacy #RareDisease #GeneticCondition #MedicalInnovation #PatientStory #ChronicIllness #LivingWithHemophilia #BleedingDisorders #GeneTherapyTrial #IrreversibleDecision #SharedDecisionMaking #PatientEmpowerment #MedicalBreakthrough #ClinicalTrial #HealthcareInnovation #PatientAdvocate #RareDiseaseCommunity #Resilience #MedicalDecisions