CIO: Healthcare-Specific LLM Deployment and Fine-Tuning

The strategic calculus for healthcare LLM deployment has shifted decisively in the last 60 days, with new research challenging the foundational assumption that traditional task-based AI monitoring works for generalist models, and early enterprise deployments at Penn Medicine, Cedars-Sinai, and others establishing reference architectures for PHI-safe integration. For CIOs, the question is no longer whether to deploy clinical LLMs, but how to govern them against newly documented failure modes — including a 15% higher rate of critical medical omissions in general-purpose models versus purpose-built clinical AI.