Clinical Trial Representativeness in Oncology

Using myeloma as an example, why trial representativeness has a meaningful clinical impact in oncology DETERMINATION trial: https://www.nejm.org/doi/full/10.1056/NEJMoa2204925 Blood letter: https://ashpublications.org/blood/article/137/21/2987/475530/Incidence-of-skin-hyperpigmentation-in-Black