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Podcast Episode

Dr. Tania Dempsey, MD: Mast Cell Activation Syndrome, PMOS, and the Hidden Cause of Women's Chronic Symptoms

Longevity Optimization with Kayla Barnes-Lentz·Kayla Barnes-Lentz·11 September 2026·1h 17m

About this episode

Most women who deal with unexplained allergies, stubborn inflammation, heavy periods or a PMOS (formerly PCOS) diagnosis are never told to look at the same underlying cause: an immune cell most doctors were never taught to test for.Dr. Tania Dempsey, MD, trained in internal medicine at Johns Hopkins before leaving conventional practice to focus on mast cell activation syndrome, a condition she believes explains far more chronic illness in women than most doctors realize. She's the founder of The AIM Center for Personalized Medicine and helped found the International Society for Mast Cell Activation Syndromes, where she now serves as treasurer.This isn't some rare, fringe diagnosis. Dr. Dempsey estimates it may affect as many as one in five people, and in women it hides behind a long list of other labels, PMOS, endometriosis, hypermobility, unexplained heavy periods, that rarely get connected back to the same root.Optimize your sleep with the Eight Sleep Pod.Get up to $350 off at https://www.eightsleep.com/Kayla with code “KAYLA”.Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.https://kayla-barnes-lentz.circle.so/female-longevity-communityThis conversation exploresThe overreaction inside your immune system that never fully resetsWhy PMOS and mast cell activation almost always show up togetherThe natural blood thinner behind unusually heavy periodsWhere treatment actually starts, from vitamin D to advanced IV therapy Connect with Kayla:Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter:https://x.com/femalelongevityWebsite:https://www.kaylabarnes.com/Spotify:https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054Apple:https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227Follow Her Female Protocol: https://www.protocol.kaylabarnes.com Connect with Dr. Tania Dempsey:Instagram: https://www.instagram.com/drtaniadempseymd/LinkedIn: https://www.linkedin.com/in/taniadempsey/Website: https://drtaniadempsey.com/YouTube: https://www.youtube.com/@DrTaniaDempsey #longevity #womenslongevity #mastcellactivationsyndrome #mcas #pmos #histamineintolerance #endometriosis #womenshealth #chronicillness #rootcausemedicine #hormonehealth #inflammation